Bone adaptation and comparative morphology

Peer-reviewed publications

Skedros JG, Sybrowski CL, Parry, TR and Bloebaum RD, and Hofmann AA. Regional Differences in Cortical BoneOrganization and Microdamage Prevalence in Rocky Mountain Mule Deer. Anat Rec. 274A:837–850. PDF

Kuo TY, Skedros JG, Bloebaum RD, and Hofmann AA. 2003. Direct and indirect measurement of femoral anteversion. In Press

Skedros JG. 2003. Analysis of mineral content in tension and compression trabecular bone tracts of a skeletal bending system resembling a simple cantilevered beam. Submitted.

Skedros JG, Hunt KJ, Hughes PE and Winet HW. 2003. Ontogenetic and Regional Morphologic Variations in the Turkey Ulna Diaphysis: Implications for Functional Adaptation of Cortical Bone. Anat Rec.

Skedros JG, Hunt KJ and Bloebaum RD. 2003. Implications of Loading History on Structural and Material Characteristics of Cortical Bone: The Ontogenetic Development of the Mule Deer Calcaneus. J Morphol. (submitted)

Skedros JG, Mason MW, and Bloebaum RD. 2001. Modeling and remodeling in a developing artiodactyl calcaneus: A model for evaluating Frost's Mechanostat hypothesis and its corollaries. Anat Rec, 263:167-185

Su SC, Skedros JG, Bachus KN, Bloebaum RD. 1999. Loading conditions and cortical bone construction of an artiodactyl calcaneus. J Exp Biol. 202 Pt 22:3239-54.

Kuo TY, Skedros JG, Bloebaum RD. 1998. Comparison of human, primate, and canine femora: implications for biomaterials testing in total hip replacement. J Biomed Mater Res. 40(3):475-89.

Skedros JG, Su SC, Bloebaum RD. 1997. Biomechanical implications of mineral content and microstructural variations in cortical bone of horse, elk, and sheep calcanei. Anat Rec. 249(3):297-316.

Skedros JG, Mason MW, Nelson MC, Bloebaum RD. 1996. Evidence of structural and material adaptation to specific strain features in cortical bone. Anat Rec. 246(1):47-63.

Mason MW, Skedros JG, Bloebaum RD. 1995. Evidence of strain-mode-related cortical adaptation in the diaphysis of the horse radius. Bone. 17(3):229-37.

Skedros JG, Mason MW, Bloebaum RD. 1994. Differences in osteonal micromorphology between tensile and compressive cortices of a bending skeletal system: indications of potential strain-specific differences in bone microstructure. Anat Rec. 239(4):405-13.

Skedros JG, Bloebaum RD, Mason MW, Bramble DM. 1994. Analysis of a tension/compression skeletal system: possible strain-specific differences in the hierarchical organization of bone. Anat Rec. 239(4):396-404.

Abstracts

 

Backscattered electron imaging and bone

Peer-reviewed publications

Skedros JG, Holmes JL, Vajda EG and Bloebaum RD. 2005. Cement Lines of Secondary Osteons in Human Bone Are Not Mineral-Deficient: New Data in a Historical Perspective. Anat Rec. 286A:781–803. PDF

Vajda EG, Humphrey S, Skedros JG, and Bloebaum RD 1999. Influence of topography and specimen preparation on backscattered electron images of bone. Scanning, 21:379-386.

Vajda EG, and Skedros JG 1999. Letter to the editor. Bone, 24:619-620.

Vajda EG, Skedros JG, and Bloebaum RD. 1998. Errors in quantitative backscattered electron analysis of bone standardized by energy-dispersive X-ray spectrometry. Scanning, 20:527-535.

Bloebaum RD, Skedros JG, Vajda EG, Bachus KN and Constantz BR. 1997. Determining mineral content variations in bone using backscattered electron imaging. Bone, 20: 485-490.

Vajda EG, Bloebaum RD, Skedros JG. 1996. Validation of energy dispersive X-ray spectrometry as a method to standardize backscattered electron images of bone. Cells and Materials, 6:79-92.

Vajda EG, Skedros JG, and Bloebaum RD. 1995. Consistency in calibrated backscattered electron images of calcified tissues and mineral analyzed in multiple imaging sessions. Scanning Microscopy, 9: 741-755.

Skedros JG, Bloebaum RD, Bachus KN, Boyce TM, and Constantz B. 1993. Influence of mineral content and composition on graylevels in backscattered electron images of bone. J. Biomedical Materials Research, 27:57-64.

Skedros JG, Bloebaum RD, Bachus, KN, and Boyce TM. 1993. The meaning of graylevels in backscattered electron images of bone. J. Biomedical Materials Research, 27:47-56.

Boyce TM, Bloebaum RD, Bachus KN, and Skedros JG. 1990. Reproducible method for calibrating the backscattered electron signal for quantitative assessment of mineral content in bone. Scanning Microscopy, 4(3):591-603.

Abstracts

Clinical -- shoulder and elbow

Peer-reviewed publications

Burkhead WZ Jr, Skedros JG, O’Rourke PJ, Arcand MA, and Pierce WA. 2003. Experimental comparison of failure strengths of conventional rotator cuff repairs to a technique using a combination of transosseous sutures and suture anchors. Submitted.

Skedros JG, O’Rourke PJ, Zimmerman JM, Burkhead WZ Jr. 1999. Alternatives to Replacement Arthroplasty for Glenohumeral Arthritis. In: Iannotti JP and Williams GR (eds): Disorders of the Shoulder: Diagnosis and Management. Chapter 18. Lippincott Williams and Wilkins, Philadelphia, PA, pp. 485-499.

Zimmerman JM, Skedros JG, O’Rourke PJ, Dean MT, Burkhead WZ Jr. 1999. Rehabilitation and Nonoperative Treatment. In: Warren RF, Craig EV, and Altchek DW (eds): The Unstable Shoulder. Chapter 11. Lippincott-Raven Publishers, Philadelphia, PA, pp. 177-188.

Zeman CA, Arcand MA, Cantrell JS, Skedros JG, Burkhead WZ Jr. 1998. The Rotator Cuff-Deficient Arthritic Shoulder: Diagnosis and Surgical Management. J Am Academy Orthop Surgeons. 7:337-348.

Abstracts

Clinical -- osteoporosis

Peer-reviewed publications

Skedros JG and Holyoak JD. 2003. Knowledge and Opinions of Orthopaedic Surgeons Concerning Initiation of Medical Treatment for Patients with Osteoporotic Fractures. JAMA. (Submitted)

Skedros JG. 2003. The Orthopaedic Surgeon’s Role in Diagnosing and Treating Patients with Osteoporotic Fractures: Standing Discharge Orders may be the Solution for Timely Medical Care. New Engl J Med (Submitted)

Skedros JG. 2003. The Orthopaedic Surgeon as a Clinical Densitometrist: Evaluation of Cost and Time Effectiveness.

Abstracts